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Methadone is contraindicated hinein patients with a known hypersensitivity to methadone hydrochloride or any other ingredient in methadone hydrochloride tablets.
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Benztropine and amitriptyline. Taking these drugs with methadone may cause urinary retention (not being able to fully empty your bladder), constipation, and slowed movement rein your stomach and bowels. This can lead to a severe bowel obstruction.
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Below is a Trick of medications that can interact with methadone. This Hinterlist doesn’t contain all drugs that may interact with X drug.
Proper assessment of the patient, proper prescribing practices, periodic re-evaluation of therapy, and proper dispensing and storage are appropriate measures that help to Grenzwert abuse of opioid drugs.
Methadone is also used to manage drug addiction. If you have an addiction to another opioid, your doctor may give you methadone to prevent you from having severe withdrawal symptoms.
Methadone is a mu-agonist opioid with an abuse liability similar to that of morphine and is a Schedule II controlled substance. Methadone, like morphine and other opioids used for analgesia, has the potential for being abused and is subject to criminal diversion.
Several studies have suggested that infants born to narcotic-addicted women treated with methadone during all or parte of pregnancy have been found to have decreased fetal growth with reduced birth weight, length, and/or head circumference compared to controls.
However, if the use of methadone is necessary hinein such patients, a sensitivity test should be performed rein which repeated small, incremental doses of methadone are administered over the course of several hours while the patient's condition and vital signs are under careful observation.
The Tarif at which methadone is decreased should be determined separately for each patient. The dose of methadone can Beryllium decreased on a daily basis or at 2-day intervals, but the amount of intake should remain sufficient to keep withdrawal symptoms at a tolerable level. Rein hospitalized patients, a daily reduction of 20% of the total daily dose may be tolerated. Rein ambulatory Erhaltungstherapie mit Methadontabletten patients, a somewhat slower schedule may be needed.
The safety and effectiveness of this drug hasn’t been established rein children. It shouldn’t be used hinein children younger than 18 years.
Dosage adjustment using higher doses or administering the daily dose rein divided doses may Beryllium necessary hinein pregnant women treated with methadone (see CLINICAL PHARMACOLOGY and DOSAGE AND ADMINISTRATION).
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